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Macrophages are known to express creatine kinase 290 and to take creatine up from a medium initially by a sodium dependent mechanism (likely the creatine transporter) in a saturable manner, 437 with a second component that requires there to be no concentration gradient to work against (likely p***ve diffusion) but tends to only account for up to 10% of total uptake in the physiological range (20-60µM).


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